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Based on the spatio-temporal coding characteristics of frontotemporal network, this paper explores the mechanism of five-tone speech training in reshaping language fluency function

Based on the spatio-temporal coding characteristics of frontotemporal network, this paper explores the mechanism of five-tone speech training in reshaping language fluency function

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500112570
Enrollment
Unknown
Registered
2025-11-17
Start date
2025-12-01
Completion date
Unknown
Last updated
2025-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Aphasia

Interventions

Experimental group:'Five Tones ' therapy based on melody intonation training mode
health education.
Positive control group:Melody intonation therapy
health educationpositive control group.
health education

Sponsors

Rehabilitation Hospital Affiliated to Fujian University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1.In line with the diagnostic points of stroke in Chinese and Western medicine, and confirmed by brain CT or MRI examination, it belongs to the left hemisphere stroke of the brain 2.Patients with non-fluent aphasia diagnosed by Western Aphasia Battery ( WAB ) and BDAE grade 1-5 3.The course of disease > 2 weeks 4.Right handedness 5.Age 18-70 years old 6.Stable vital signs, clear consciousness, no obvious audio-visual impairment 7.Through ethical review, and patients voluntarily signed informed consent, can understand and cooperate with the rehabilitation evaluation and treatment of this test.

Exclusion criteria

Exclusion criteria: 1.Primary aphasia, or other diseases ( such as : brain trauma, brain tumors, brain infections, etc. ) caused by non-stroke aphasia 2.Patients with speech disorder, or severe cognitive dysfunction, or unclear consciousness caused by organic lesions of articulation organs, who could not cooperate with language function examination and complete relevant intervention treatment 3.Patients with severe auditory or visual dysfunction 4.There were serious complications of stroke ( such as lower extremity deep venous thrombosis, severe respiratory infection, upper gastrointestinal bleeding, etc. ) 5.Suffering from other serious diseases ( such as : severe heart and lung dysfunction, epilepsy, malignant tumors, and heart, liver, kidney failure, etc. ) 6.Suffering from severe mental illness ( e.g. depression, anxiety, schizophrenia, etc. ) 7.Nuclear magnetic contraindications ( such as : metal dentures, metal implants, etc. ). Anyone with one of the above conditions is excluded from this study.

Design outcomes

Primary

MeasureTime frame
Speech fluency;Semantic Fluency;

Secondary

MeasureTime frame
Boston Diagnostic Aphasia Severity Rating;Minimum Mental State;Western Aphasia;Chinese Functional Communication ;

Countries

China

Contacts

Public ContactHuang Jia

Rehabilitation Hospital Affiliated to Fujian University of Traditional Chinese Medicine

jasmine1874@163.com+86 182 5017 8180

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026