Parkinson's disease
Conditions
Interventions
Experimental group:rTMS+tDCS+situational interactive rehabilitation training
Control group:Sham rTMS + sham tDCS + situational interactive rehabilitation training
Sponsors
The First Hospital of Hebei Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Diagnosis meets the standards of the "Chinese Parkinson's Disease Diagnostic Criteria (2016 edition)"; 2. H-Y stage = 3; 3. Vital signs are stable; 4. Able to walk independently and safely without assistance or the use of a cane, and can independently perform standing up, sitting, and standing movements; 5. Agree to undergo systematic motor function assessment, able to understand instructions from the therapist or device, and can complete the required movements; 6. Agree to participate in this study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Those with secondary Parkinson's syndrome or overlapping Parkinson's syndrome; 2. Those with other severe physical or mental illnesses; 3. Individuals with metal implants in the skull; 4. Those using implanted electronic devices; 5. Individuals with concurrent tumor diseases; 6. Those with a history of epileptic seizures; 7. Individuals with other intracranial organic diseases; 8. Those with a history of cranial surgery or significantly increased intracranial pressure; 9. Individuals prone to bleeding; 10. Patients with local skin damage, inflammation, or hyperesthesia at the stimulation site.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Berg Balance Scale Score;Unified Parkinson’s Disease Rating Scale Part III,MDS-UPDRS ?;Balance evaluation;Gait kinematics analysis;Resting state EEG;Transcranial magnetic synchronized EEG; | — |
Secondary
| Measure | Time frame |
|---|---|
| Motor Evoked Potentials, MEP; | — |
Countries
China
Contacts
Public ContactWang Yahui
The First Hospital of Hebei Medical University
Outcome results
None listed