craniocerebral surgery
Conditions
Interventions
Ropivacaine group:0.5% Ropivacaine is used to scalp nerve block
Bupivacaine liposome group:0.665mg/ml of liposomal bupivacaine injection is used for scalp nerve block
Sponsors
huashan hospital fudan university
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Age > 18 years; 2. Patients scheduled for elective craniotomy neurosurgery with tumours located at or above the supraorbital notch; 3. American Society of Anesthesiologists (ASA) physical status classification I–III; 4. Patients must be conscious and able to provide informed consent preoperatively; 5. Informed consent must be signed by the patient or their legal representative.
Exclusion criteria
Exclusion criteria: 1. Hypersensitivity to bupivacaine or similar local anaesthetics; 2. Severe respiratory, hepatic or renal impairment; 3. Coagulation disorders; 4. Mini-Mental State Examination (MMSE) score < 18; 5. Chronic headache; 6. Infection at injection site; 7. Participation in other clinical research trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative pain score; | — |
Secondary
| Measure | Time frame |
|---|---|
| length of stay;CRP;MAP changes during the surgery;Total consumption of opioid drugs during the operation;HR changes during the surgery;PONV;Consumption of NSAINDS ; | — |
Countries
China
Contacts
Public ContactLi Li
huashan hospital fudan university
Outcome results
None listed