Tethered Cord Syndrome
Conditions
Interventions
Sponsors
Shenzhen Second People's Hospital
Eligibility
Sex/Gender
All
Age
6 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age >= 6 years 2. Meet the clinical-radiological diagnosis criteria of TCS. Have at least one of the following radiological evidence: low conus (usually 2 mm or fatty signal), traction caused by spinal cord lipoma/adhesions, adhesion signs resulting from previous surgery; and combine at least one clinical manifestation (such as lumbosacral/lower limb pain, lower limb sensory/motor disorder, gait abnormality, urinary and fecal function disorder, etc.). 3. Have not received spinal cord tethering surgery before. 4. Can independently complete or complete the subjective scale with the assistance of a guardian. 5. Sign a written informed consent, and the patient/ guardian agrees to the surgery and participates in the clinical study.
Exclusion criteria
Exclusion criteria: 1. Inability to complete the subjective assessment scales or adhere to the follow-up schedule as required by the study protocol. 2. Presence of concomitant neurological disorders capable of independently causing symptoms similar to TCS and which are uncontrolled during the study period (e.g., acute/active myelitis, progressive neurodegenerative diseases, acute brain or spinal cord injury, space-occupying lesions). 3. Contraindication to or inability to undergo general anesthesia with endotracheal intubation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Klinge 15-item scale scores;PedsQL Spinal Cord Injury Module scores; | — |
Secondary
| Measure | Time frame |
|---|---|
| PHQ-9/GAD-7 scores;Physical examination scale scores; | — |
Countries
China
Contacts
Public ContactZheng Wenjian
Shenzhen Second People's Hospital
Outcome results
None listed