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Multi-center, Observational Study of Teclistamab or Talquetamab in The Treatment of Multiple Myeloma Patients in China

Multi-center, Observational Study of Teclistamab or Talquetamab in The Treatment of Multiple Myeloma Patients in China

Status
Active, not recruiting
Phases
Phase 4
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500112479
Enrollment
Unknown
Registered
2025-11-14
Start date
2025-12-01
Completion date
Unknown
Last updated
2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Multiple myeloma

Interventions

Teclistamab group:NA
Talquetamab group:NA

Sponsors

Peking Union Medical College Hospital, Chinese Academy of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. =18 years old when starting treatment. 2. RRMM disease. 3. Provide a signed informed consent form (ICF) . 4. Has received/will receive = 1 dose of Teclistamab/Talquetamab.

Exclusion criteria

Exclusion criteria: Is currently participating in an interventional clinical study.

Design outcomes

Primary

MeasureTime frame
ORR according to IMWG criteria;

Secondary

MeasureTime frame
Patient demographics, clinical characteristics and treatment history.;Treatment patterns, including prior regimen, combination, dosing and treatment line;CR or better rate;VGPR or better rate;Time to first response (TTR);Time to next treatment (TTNT);Duration of response (DOR);Progression-free survival (PFS);Overall survival (OS);Incidence, severity, concomitant treatment of prophylaxis and management of adverse events (AEs), including cytokine release syndrome (CRS), immune effector cell-associated neurotoxicity syndrome (ICANS), infections, GPRC5D related AEs (skin-, nail-, and oral-related disorders), and other AEs, etc;

Countries

China

Contacts

Public ContactLi Jian

Department of Hematology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences

lijian@pumch.cn+86 186 1085 2525

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026