depressive disorder
Conditions
Interventions
HD-tDCS+iTBS group:On the basis of antidepressant drugs, HD-tDCS and iTBS was given
iTBS group:On the basis of antidepressant drugs, sham HD-tDCS and iTBS was given
drug group:On the basis of antidepressant drugs, sham HD-tDCS and sham iTBS was given
Sponsors
The Second Affiliated Hospital of Xinxiang Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: (1) Diagnosed as depression by two attending psychiatrists based on the Diagnostic and Statistical Manual of Mental Disorders (5th Edition). (2) HAMD-17 score higher than 17. (3) Aged 18 to 60, Han ethnicity. Right-handed individuals (4)Patients are taking stable antidepressant drugs (5)Patients can tolerate the treatment (6)Patients understand all the questionnaires of this study (7)Patients understand and agree to participate in this study and sign the informed consent form
Exclusion criteria
Exclusion criteria: (1) Patients have a history of epilepsy, brain tumors or other organic brain diseases (2) Patients have a history of exposure to psychoactive substances or other mental illnesses (3) There are metal implants such as cochlear implants, artificial heart valves, artificial joints, and pacemakers in the body (4) Patients who have received tDCS/TMS/ECT treatment within the last 3 months (5) Positive HCG/ urine HCG test results in pregnant, lactating women or women of childbearing age during the screening period (6) In the past half month, patients have acute infections and inflammations, as well as head injuries
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The Chinese Brief Cognitive Test, C-BCT;Hamilton Depression Scale, HAMD-17;Big Five Personality Scale;electroencephalogram, EEG; | — |
Countries
China
Contacts
Public ContactJuan Li; Shina Gu
The Second Affiliated Hospital of Xinxiang Medical University
Outcome results
None listed