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Brain-gut axis integration based on multimodal CT/MRI: A functional imaging study exploring digestive system diseases and their comorbid neurological disorders and sleep disorders

Brain-gut axis integration based on multimodal CT/MRI: A functional imaging study exploring digestive system diseases and their comorbid neurological disorders and sleep disorders

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500112465
Enrollment
Unknown
Registered
2025-11-14
Start date
2025-12-01
Completion date
Unknown
Last updated
2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Meets the diagnostic criteria for nervous system disorders (G00-G99) in the tenth edition of the International Classification of Diseases (ICD-10), non-organic sleep disorders (F51), or primary insomnia disorders (complaints of difficulty falling asleep, maintaining sleep, or waking up early, lasting >= 3 months, and >= 3 times per week) in DSM-5

Interventions

Digestive system disease group:None
COM group:None

Sponsors

The First Affiliated Hospital of Zhengzhou University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1.Digestive system diseases with gold standard or clinical diagnosis (such as gastric cancer diagnosed by pathology, duodenal ulcer diagnosed by gastroscopy, etc.); 2.Meets the diagnostic criteria for nervous system disorders (G00-G99) in ICD-10, non-organic sleep disorders (F51), or primary insomnia disorders (complaints of difficulty falling asleep, maintaining sleep, or waking up early, lasting >= 3 months, and >= 3 times per week) in DSM-5; 3.Clinical data with relevant imaging data (CT and MRI) and at least one of the following: Unified Parkinson's Disease Rating Scale, Montreal Cognitive Assessment, Pittsburgh Sleep Quality Index Scale, Self-Rating Depression Scale, Self-Rating Anxiety Scale, etc. 4.Ages 18-65, any gender. 5. Does not combine with other systemic neoplastic diseases..

Exclusion criteria

Exclusion criteria: 1.Ill-defined disease diagnosis; 2.Patients with other diseases that severely affect sleep; 3.Long-term polydrug co-users; 4. Imaging and clinical data are incomplete.

Design outcomes

Primary

MeasureTime frame
MRI?CT image evaluation;

Secondary

MeasureTime frame
Clinical features;

Countries

China

Contacts

Public ContactZihao Zhao

The First Affiliated Hospital of Zhengzhou University

zzh2020@163.com+86 371 6627 1387

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026