Skip to content

Effect of Nursing Interventions Based on PaO2/FiO2 Monitoring on Weaning Time in Patients with Severe Pneumonia: A Prospective Randomized Controlled Study

Effect of Nursing Interventions Based on PaO2/FiO2 Monitoring on Weaning Time in Patients with Severe Pneumonia: A Prospective Randomized Controlled Study

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500112462
Enrollment
Unknown
Registered
2025-11-14
Start date
2025-12-01
Completion date
Unknown
Last updated
2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Severe Pneumonia

Interventions

control group:The blood gas analysis results presented on the system interface show only the raw numerical values of PaO2 and FiO2. The system does not generate pop-up alerts to prompt nurses to enter
Intervention Group: the nursing electronic workstation displayed the PaO?/FiO? ratio (the oxygenation index, i.e., the ratio of arterial partial pressure of oxygen to fraction of inspired oxygen, used

Sponsors

The Second Affiliated Hospital of Anhui Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: (1) >= 18 years old; (2) Meeting the IDSA/ATS 2019 diagnostic criteria for severe pneumonia; (3) Endotracheal intubation with mechanical ventilation = 72 hours; (5) Informed consent signed by a legal representative.

Exclusion criteria

Exclusion criteria: (1) Chest trauma or post-thoracic surgery; (2) Chronic respiratory failure requiring long-term home ventilation; (3) Acute cardiac dysfunction.

Design outcomes

Primary

MeasureTime frame
duration of mechanical ventilation;28-day Ventilator-Free Days;

Secondary

MeasureTime frame
Nurses proactively adjust the frequency of physical therapy.;Incidence of Ventilator-Associated Pneumonia;Length of Hospital Stay;Length of ICU Stay;Total Hospitalization Costs ;Average Daily Costs;In-hospital Mortality:;28-day Mortality;

Countries

China

Contacts

Public ContactXueli Jia

The Second Affiliated Hospital of Anhui Medical University

512900269@qq.com+86 138 5602 3631

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026