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Construction of an early warning model based on extravascular lung water index and ventricular time integral: risk prediction of pulmonary edema after cesarean section under general anesthesia in preeclampsia

Construction of an early warning model based on extravascular lung water index and ventricular time integral: risk prediction of pulmonary edema after cesarean section under general anesthesia in preeclampsia

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500112453
Enrollment
Unknown
Registered
2025-11-14
Start date
2025-11-17
Completion date
Unknown
Last updated
2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

preeclampsia

Interventions

Observation group:Not applicable

Sponsors

Women’s Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: 1. Inclusion criteria: (1) Preeclampsia patients aged 18-45 years with ASA grade III (2)scheduled for a cesarean section under general anesthesia.

Exclusion criteria

Exclusion criteria: 2. Exclusion criteria: (1)Parturient women with cardiopulmonary, liver and kidney dysfunction (2)There are severe infections, dehydration, electrolyte disturbances and maternal shock (3)History of allergy to hydroxyethyl starch HES (130/0.4), sodium lactate Ringer's injection or ultrasonic couplants (4)Use of drugs that affect cardiac function, such as beta antagonists, calcium channel blockers, digitalis, etc. (5)Severe brain damage, confusion, respiratory depression (6)Pregnant women who have participated in other clinical trials within 3 months prior to enrollment and pregnant women who are participating in other clinical trials (7)Pregnant women who, in the judgment of the physician responsible for the trial, may be at increased risk for the trial or may not have access to adequate trial data

Design outcomes

Primary

MeasureTime frame
Extravascular lung water index;Ventricular time integral;

Secondary

MeasureTime frame
Body mass index (BMI);Gestational age;Albumin;Brain natriuretic peptide;

Countries

China

Contacts

Public ContactHuiying Zhang

Women’s Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital

279763402@qq.com+86 138 5169 0367

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026