Postoperative delirium
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Aged 65–80 years; (2) Scheduled for elective cardiac valve replacement under cardiopulmonary bypass; (3) Provided written informed consent for study participation.
Exclusion criteria
Exclusion criteria: (1) Concomitant neurologic disorders including cerebral infarction, Alzheimer’s disease, or other forms of dementia; (2) Severe visual or auditory impairment; (3) Antibiotic use within 7 days before surgery; (4) History of alcohol or drug abuse; (5) Subjects lacking decision-making capacity or with psychiatric illness or other vulnerable populations.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of postoperative delirium ; | — |
Secondary
| Measure | Time frame |
|---|---|
| postoperative in-hospital day;Postoperative all-cause mortality;Length of intensive care unit stay;Cause and time of death;POD phenotype; | — |
Countries
China
Contacts
Second Affiliated Hospital of Army Medical University,PLA, China Xinqiao zheng street CHONGQING 400038, China