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Study on the efficacy and safety of radio-frequency micro-needle combined with botulinum toxin in the treatment of orbital aging

Study on the efficacy and safety of radio-frequency micro-needle combined with botulinum toxin in the treatment of orbital aging

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500112439
Enrollment
Unknown
Registered
2025-11-13
Start date
2025-11-13
Completion date
Unknown
Last updated
2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Periorbital aging

Interventions

Radio-frequency micro-needle therapy group:None
Radio-frequency micro-needle combined with botulinum toxin therapy:None
Botulinum toxin treatment group:None

Sponsors

The First Affiliated Hospital of the Chinese People's Liberation Army Military University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
30 Years to 50 Years

Inclusion criteria

Inclusion criteria: 1.The dynamic wrinkle rating around the orbit is >= 4 points, suitable for subjects with moderate or severe wrinkles; 2.Patients who have not received other facial anti-aging treatments within 3 months, and patients who have not received injections of botulinum toxin around the eyes within 6 months; 3.Age range: 30-50 years old; 4.The subjects have good compliance and the follow-up data is complete and authentic.

Exclusion criteria

Exclusion criteria: 1.Patients with missing test data.

Design outcomes

Primary

MeasureTime frame
Periorbital aging (crow's feet) degree ;

Secondary

MeasureTime frame
Adverse reaction;Skin moisture content, elasticity, and loss of moisture through the epidermis;Global Aesthetic Improvement ;Static wrinkles around the orbit (infraorbital wrinkles);

Countries

China

Contacts

Public ContactGe Lan

The First Affiliated Hospital of the Chinese People's Liberation Army Military University

43793340@qq.com+86 23 68765784

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026