Stroke
Conditions
Interventions
tACS group in M1 region:Application of tACS intervention in M1 region
tACS group in cerebellar:Application of tACS to the cerebellum
Sham stimulation group:Electrodes are placed without applying current.
Healthy control group:no
Sponsors
Tianjin Union Medical Center
Eligibility
Sex/Gender
All
Age
40 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Age 40–80 years; 2. Diagnosed via CT or MRI as a first-time unilateral ischaemic or haemorrhagic stroke; 3. Disease stage: acute or subacute phase; 4. Montreal Cognitive Assessment (MoCA) score =26; 5. Presenting with varying degrees of unilateral upper limb motor impairment; 6. Signed informed consent for the trial.
Exclusion criteria
Exclusion criteria: 1. Cases involving bilateral cerebral hemispheres, brainstem, or cerebellar stroke; 2. Presence of pacemakers or intracranial metallic implants. 3. Individuals with psychiatric disorders or a history thereof; 4. Those with multiple organ injuries; 5. Patients experiencing post-stroke depression; 6. Individuals with a history of epilepsy, neurosurgical procedures, or traumatic brain injury; 7. Subjects with poor compliance who are unable to complete the trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Electroencephalogram(EEG);Magnetic Resonance Imaging(MRI);Wolf motor function test(WMFT); | — |
Secondary
| Measure | Time frame |
|---|---|
| Fugl-Meyer Assessment of Motor Function(FMA-UE);motor activity log( MAL);Modified Ashworth Scale(MAS);Box and Block Test; | — |
Countries
China
Contacts
Public ContactChunfang Wang
Department of Rehabilitation The First Affiliated Hospital of Nankai University
Outcome results
None listed