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Evaluation of clinical effects of different proportions of CGF and Bio-Oss compound guided jaw regeneration

Evaluation of clinical effects of different proportions of CGF and Bio-Oss compound guided jaw regeneration

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500112418
Enrollment
Unknown
Registered
2025-11-13
Start date
2025-04-10
Completion date
Unknown
Last updated
2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cyst of jaw

Interventions

Group A experimental group:CGF gel was weighed in the required proportion and removed, and cut into particles of about 1mm size (cgf:bio-oss bone meal mass ratio was 1:1), mixed with bone meal, stirre
Group B experimental group:CGF gel was weighed in the required proportion and removed, and cut into particles of about 1mm size (cgf:bio-oss bone meal mass ratio was 2:1), mixed with bone meal, stirre
Group C experimental group:CGF gel was weighed in the required proportion and removed, and cut into particles of about 1mm size (cgf:bio-oss bone meal mass ratio was 4:1), mixed with bone meal, stirre
Control group:Simply fill CGF gel, cover the surface with bio-gide biofilm, and cover the top of the biofilm and the bottom of the gum with CGF membrane.The surface of the CGF covered with bio-gide bi

Sponsors

Bengbu Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1.Age: 18 to 60 years old; 2. The diameter of the jawbone cyst is 2.0-4.0cm. 3. No concomitant infections; 4. The overall condition is good, with no contraindications for related surgeries. 5. Be informed of the treatment-related circumstances and sign the surgical consent form before the operation.

Exclusion criteria

Exclusion criteria: 1. Those who suffer from systemic diseases that affect bone healing and whose conditions are poorly controlled; 2. Patients with severe segmental defects after the removal of jawbone cysts or those involving the nasal cavity and maxillary sinus; 3. Patients who are unable to prepare sufficient autologous platelet concentrated products due to poor blood quality of their own.

Design outcomes

Primary

MeasureTime frame
Bone tissue regeneration;

Secondary

MeasureTime frame
Degree of postoperative inflammation;Degree of swelling;Keratinized gingival width;The degree of postoperative pain;

Countries

China

Contacts

Public ContactShan Zhixuan

Bengbu Medical University;Maanshan People's Hospital

2931732496@qq.com+86 555 822 2805

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026