None listed
Conditions
Interventions
Bupivacaine liposome group for iliac fascial space block above the inguinal ligament in elderly patients undergoing total hip arthroplasty:Intervention name: Liposomal bupivacaine supra-inguinal fasci
if failed, it was increased by 2%. The trial was terminated after 7 alternating "success–failure" outcomes. Block success was defined as a resting NRS =2, movement NRS =3, =2 PCIA presses, and no resc
Sponsors
Luxian People's Hospital
Eligibility
Sex/Gender
All
Age
60 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1. Age 60–90 years; 2. ASA classification I–III; 3. Scheduled for primary unilateral total hip arthroplasty; 4. Signed informed consent.
Exclusion criteria
Exclusion criteria: 1. Allergy to bupivacaine or other amide-type local anesthetics; 2. Infection or anatomical abnormalities at the puncture site; 3. Coagulation dysfunction; 4. Long-term use of opioids or sedatives; 5. Severe organic lesions or dysfunction of the heart, lungs, liver, kidneys, etc.; 6. Neurological, psychiatric, or cognitive dysfunction; 7. Those who refuse to participate will also be excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The median effective concentration (EC50) and 95% confidence interval of bupivacaine liposomes in S-FICB for elderly patients undergoing total hip arthroplasty;Muscle Strength Grading (MRC); | — |
Secondary
| Measure | Time frame |
|---|---|
| Resting and activity NRS scores;Sufentanil dosage for postoperative patient-controlled intravenous analgesia (PCIA);First Out-of-Bed Time;Length of hospital stay;Bromage Score; | — |
Countries
China
Contacts
Public ContactHe Tianping
Luxian People's Hospital
Outcome results
None listed