Helicobacter pylori
Conditions
Interventions
Observation group:None
Sponsors
The Affiliated Hospital of Xuzhou Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age >=18 years old; 2. 13C-UBT and gastroscopy were performed at the same time.
Exclusion criteria
Exclusion criteria: 1. Patients in a state of diarrhea and/or constipation; 2. Patients who cannot cooperate and/or have incomplete clinical information; 3. Repeat patients; 4. Children and adolescents aged less than 18 years; 5. patients after gastrointestinal surgery; 6. Severe gastrointestinal complications, such as pyloric obstruction and active bleeding under endoscopy; 7. Complicated with other serious gastrointestinal diseases, such as ulcerative colitis, Crohn's disease, etc. 8. Patients with other serious liver and kidney diseases, serious heart and lung diseases, advanced tumors, hematological and hematopoietic system diseases, or serious or progressive diseases of other systems; 9. Patients with comorbid mental disorders who are unable to cooperate; 10. Pregnant or lactating women or those who plan to have children in the near future (within 1 year); 11. Previous allergic reactions or drug contraindications to study drugs; 12. Patients who were deemed unfit to participate in the study by other investigators.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Helicobacter pylori eradication success rate;Clarithromycin resistance rate;Quinolone resistance rates;Results of noninvasive molecular detection of Helicobacter pylori in patients with cut-off value of 13C breath test; | — |
Secondary
| Measure | Time frame |
|---|---|
| H. pylori gene sequencing results in fecal samples;The relationship between previous H. pylori infection history, eradication history, infection history of family members and drug resistance mutations was analyzed;To investigate the correlation between the Ct value of PCR and the DOB value of 13C-UBT in the detection of H. pylori in stool samples;The H.plyori heteroresistance within the same patient;Helicobacter pylori susceptibility test results from gastric mucosa culture; | — |
Countries
China
Contacts
Public ContactFei Sujuan
The Affiliated Hospital of Xuzhou Medical University
Outcome results
None listed