Emergence agitation,EA
Conditions
Interventions
Control group:No premedication + Intravenous injection of normal saline half an hour before the end of surgery.
Esketamine group:No premedication+Administer Esketamine Injection Half an Hour Before Surgery Conclusion
Preconditioning group:Preoperative Nasal Tamponade with Sponge and Mouth-Breathing Training + Intravenous Normal Saline Injection Half an Hour Before Surgery Conclusion
Preconditioning+Esketamine group:Preoperative Nasal Tamponade with Sponge and Mouth-Breathing Training + Administer Esketamine Injection Half an Hour Before Surgery Conclusion
Sponsors
The Third Affiliated Hospital of Southern Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.?Elective endoscopic sinus surgery under general anesthesia; 2.Aged 18 and above; 3.ASA classification I - II; 4.No respiratory or circulatory system disorders; 5.Preoperative Anxiety Scale (PAS-7) score < 8; 6.Normal liver and kidney function;
Exclusion criteria
Exclusion criteria: 1.patients undergoing secondary or multiple nasal surgeries; 2.Contraindicated in individuals with known hypersensitivity to the investigational drug or other anesthetic agents; 3.Patients diagnosed with psychiatric disorders, neurological diseases, and those on long-term psychotropic medication; 4.Preoperative Anxiety Scale (PAS-7) score >= 8; 5.Participation in other clinical trials within one month before the start of this study; 6.Enrollment in any other clinical trial within the month preceding the initiation of this study;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sedation-agitation Scale ,SAS; | — |
Secondary
| Measure | Time frame |
|---|---|
| Perioperative anxiety scale,PAS-7;Wong-Baker FACES Pain Rating Scale;Time of patient extubation;Occurrence of postoperative adverse reactions; | — |
Countries
China
Contacts
Public ContactSong Fuhu
The Third Affiliated Hospital of Southern Medical University
Outcome results
None listed