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Application of a Novel Flexible VOCs Gas Sensor Array Sensing System in Clinical Phenotype Identification and Dynamic Risk Early Warning of COPD

Application of a Novel Flexible VOCs Gas Sensor Array Sensing System in Clinical Phenotype Identification and Dynamic Risk Early Warning of COPD

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500112370
Enrollment
Unknown
Registered
2025-11-13
Start date
2025-12-01
Completion date
Unknown
Last updated
2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Obstructive Pulmonary Disease

Interventions

Gold Standard:This study adopts the comprehensive diagnostic criteria recommended by the 2025 Global Initiative for Chronic Obstructive Lung Disease (GOLD) guidelines as the clinical reference standar
Index test:The diagnostic test under evaluation in this study is the "Flexible VOCs Gas Sensor Array Sensing System based on metal oxide/conducting polymer/carbon nanomaterial composite fibers." Fabri

Sponsors

Beijing Chao-Yang Hospital, Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. COPD Case Group Inclusion Criteria: (1) Aged 40-80 years, regardless of gender. (2) Meets the GOLD 2025 diagnostic criteria for COPD (post-bronchodilator FEV1/FVC =300/µL, non-eosinophilic phenotype 0.7, FEV1% predicted >80%). (3) No history of chronic respiratory diseases or recent respiratory infections.

Exclusion criteria

Exclusion criteria: 1. COPD Case Group Exclusion Criteria: (1) Co-existing bronchial asthma, lung cancer, interstitial lung disease, or other major respiratory system diseases. (2) Use of antibiotics or systemic corticosteroids within the past month. (3) Presence of cognitive impairment, mental disorders, or restricted limb mobility that would prevent cooperation with device usage. (4) Pregnant or lactating women. 2. Healthy Control Group Exclusion Criteria: (1) Respiratory infections or systemic inflammatory diseases within the past 3 months. (2) Smoking history of >5 pack-years. (3) History of occupational exposure to dust/chemical substances.

Design outcomes

Primary

MeasureTime frame
Characteristic Exhaled VOCs Concentration Profile (SCFAs and 4-7 other target molecules);Pulmonary Function Parameters ;Induced Sputum Inflammatory Cell Differential Count;—

Secondary

MeasureTime frame
Blood Eosinophil Count;Respiratory Symptom Scores;—

Countries

China

Contacts

Public ContactLi An

Beijing Chao-Yang Hospital, Capital Medical University

bjzy818@sina.com+86 136 8113 3265

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026