Female urinary incontinence
Conditions
Interventions
Urinary incontinence group:N/A
Healthy control group:N/A
Sponsors
Hong Kong Baptist University
Eligibility
Sex/Gender
Female
Age
55 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Inclusion Criteria for Patients with Urinary Incontinence (1) Females aged >=55 years (2) Has been living in Hong Kong for one year or more. (3) Meet the diagnostic criteria for SUI, UUI, or MUI, and the symptoms of urinary incontinence have persisted for at least 6 months. (4) Able to understand and follow written and verbal instructions in Chinese or English. (5) Provide informed consent voluntarily after being fully informed 2. Inclusion Criteria for Healthy Volunteers (1) Female, aged >=55 years; (2) Has been living in Hong Kong for one year or more; (3) Able to understand and follow written and verbal instructions in Chinese or English; (4) Fully informed and voluntarily signs the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Exclusion Criteria for Patients with Urinary Incontinence (1) Diagnosed with types of urinary incontinence other than stress, urge, or mixed urinary incontinence, including those secondary to neurological or systemic diseases (such as post-stroke, post-spinal cord injury, multiple sclerosis, Alzheimer’s disease, Parkinson’s disease, or uncontrolled diabetic peripheral neuropathy), as well as the overflow incontinence. (2) Active or structural urogenital diseases (such as unrepaired vesicoureteral reflux, congenital urethral malformations, urogenital fistula, urethral diverticulum, or active pelvic malignancies). (3) Deemed by researchers to be unable to cooperate with assessments due to severe mental or physical illness. 2. Exclusion Criteria for Healthy Volunteers (1) Meet the diagnostic criteria for urinary incontinence; (2) Has a history of involuntary urine leakage, or has sought medical consultation for symptoms related to urinary incontinence; (3) Has chronic comorbidities (except for well-controlled hypertension, defined as systolic blood pressure below 140 mmHg and diastolic blood pressure below 90 mmHg, and hyperlipidemia). (4) Uses medications that affect urination or gut microbiota (including but not limited to thiazolidinediones, sodium-glucose cotransporter-2 inhibitors, anticholinergics, a- and ß-adrenergic blockers, a- and ß-adrenergic agonists, diuretic antihypertensives, antihistamines, muscarinic receptor antagonists, calcium channel blockers, angiotensin-converting enzyme inhibitors, hormone medications, neurotransmitter-related drugs, and gut microbiota modulators, etc.). (5) Deemed by researchers to be unable to cooperate with assessments due to severe mental or physical illness.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Prevalence of each urinary incontinence (UI) subtype (SUI, UUI, MUI) among older women with UI in Hong Kong;Distribution of Severity among UI Patients;Distribution of TCM Syndromes;Biomarker Profiles and Their Associations with Clinical Features in UI Patients and Healthy Controls; | — |
Secondary
| Measure | Time frame |
|---|---|
| Urinary Incontinence Knowledge Score;Barriers to Incontinence Care Seeking;Quality of Life Scores (IIQ-7, ICIQ-UI-SF);Hand Grip Strength; | — |
Countries
China
Contacts
Public ContactZhaoxiang Bian
Hong Kong Baptist University
Outcome results
None listed