Depression
Conditions
Interventions
The control group:Continuous inhalation of 50% oxygen and air mixture during the operation
The 50% nitrous oxide group:Continuous inhalation of 50% nitrous oxide and oxygen mixture during the operation
The 25% nitrous oxide group:Continuous inhalation of 25% nitrous oxide and oxygen mixture during the operation
Sponsors
Shengjing Hospital of China Medical University
Eligibility
Sex/Gender
Female
Age
45 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1.Gynecological patients undergoing elective laparoscopic total hysterectomy (with or without adnexectomy); 2.45-65 years old; 3.ASA: I~II; 4.Ability to understand and complete questionnaires independently;
Exclusion criteria
Exclusion criteria: 1.Patients with contraindications of nitrous oxide, such as otitis media?sinusitis?intestinal obstruction?acute upper respiratory tract infection?Vitamin B12 deficiency?severe obstructive sleep apnea syndrome. 2.Patients with drug abuse; 3.Combined with blood system diseases: moderate and severe anemia, megaloblastic anemia, etc; 4.Patients who refuse to participate in clinical studies; 5.Patients with severe mental illness;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Score of depression scale;Score of anxiety scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| Score of recovery quality;Adverse reactions;Pain score; | — |
Countries
China
Contacts
Public ContactYing Xu
Shengjing Hospital of China Medical University
Outcome results
None listed