Skip to content

Effect of remazolam general anesthesia on myocardial injury in elderly patients with hypertension after gastrointestinal tumor surgery

Effect of Remazolam on perioperative cardiac protection in elderly patients with hypertension undergoing gastrointestinal tumor surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500112319
Enrollment
Unknown
Registered
2025-11-12
Start date
2024-04-18
Completion date
Unknown
Last updated
2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Myocardial Injury in Non-Cardiac Surgery

Interventions

Control group:General anesthesia

Sponsors

Nanjing Gulou Hospital Group Yizheng Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to 90 Years

Inclusion criteria

Inclusion criteria: (1) 65-90 years old; (2) BMI 18.5 ~ 28kg/m^2; (3) Have a history of hypertension, hypertension grade 1-2, low risk. Moderate risk, regular medication until the morning before surgery, ASA? to ? grade; (4) Patients with gastrointestinal tumors undergoing radical surgery; (5) Understand and agree with the anesthesia and research protocol: (6) actively cooperate with the data collection and postoperative follow-up during this study.

Exclusion criteria

Exclusion criteria: (1)allergic to the drugs used in the study; (2) People with unclear consciousness or cognitive dysfunction; (3) Patients with difficult airway; (4) History of severe cardiopulmonary renal dysfunction, blood system and endocrine diseases: (5) smoking patients (smoking for 6 consecutive months before surgery and more than 5 cigarettes/day); (6) Alcoholism, long-term use of analgesic drugs, etc.

Design outcomes

Primary

MeasureTime frame
Cardiac muscle injury;

Secondary

MeasureTime frame
Blood glucose;lactic acid;partial pressure of carbon dioxide;VAS;Calculate the total amount of norepinephrine used during the surgeries for the two groups;

Countries

China

Contacts

Public ContactMatingting

Nanjing Gulou Hospital Group Yizheng Hospital

279474877@qq.com+86 182 2590 9566

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026