Prostate cancer, early symptoms 1. Urination problems: frequent urination, urgency, thin urine flow, difficulty urinating, frequent nighttime awakenings, etc. This is because the prostate surrounds the urethra, and tumor growth can compress the urethra. 2. Hematuria or Hematospermia: Blood stains in urine or semen may cause the urine to appear pink, red, or cola colored. 3. Sexual dysfunction: Ere
Conditions
Sponsors
Shanghai Fifth Peoople's Hospital
Eligibility
Sex/Gender
Male
Age
60 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. Prostate cancer diagnosis: Confirmed through physical examination, pathology and imaging studies at this hospital, with a Gleason score <=7 and meeting criteria for LRP surgery; 2. Age and body weight: Aged 60–85 years, body weight 45–80kg; 3. Anaesthetic assessment: American Society of Anaesthesiologists (ASA) physical status classification I–III; 4. Informed consent: The patient and their family have been fully informed about the procedure and study details, and have voluntarily signed the informed consent form;
Exclusion criteria
Exclusion criteria: 1. Contraindications for surgery: Presence of any surgical contraindications; 2. Severe underlying conditions: Pre-operative coexisting severe cardiovascular, cerebrovascular, renal, or endocrine disorders that may compromise perioperative safety; 3. Infectious factors: Infection at the SGB puncture site, or concomitant systemic infection or acute infectious disease; 4. Psychiatric and neurological disorders: History of psychiatric illness, cognitive impairment, or inability to cooperate with the investigator; 5. Tumours and immunological factors: Concurrent malignant tumours, or autoimmune diseases; 6. Drug dependence: Long-term preoperative use of analgesic medications, or history of substance abuse.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hemodynamic monitoring;Stress and inflammatory factors;Pain indicators;Pain indicators; | — |
Secondary
| Measure | Time frame |
|---|---|
| sleep quality;cognitive function; | — |
Countries
China
Contacts
Public ContactChen Lei
Shanghai Fifth Peoople's Hospital
Outcome results
None listed