Cardiac Arrhythmia
Conditions
Interventions
Experimental group:Induction of painless gastroscopy anesthesia using ciprofol
Control group:Induction of painless gastroscopy anesthesia using propofol
Sponsors
Tacheng Prefecture People's Hospital of Ili Kazakh Autonomous Prefecture
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1.Anesthesiologists must have a valid practice certificate and be qualified to perform painless gastroscopy anesthesia; 2.Anesthesiologists and patients must cooperate to complete the entire trial and sign the informed consent; 3.Patients aged between 18 and 65 years, inclusive; 4.Patient body mass index (BMI) between 18.5–30 kg/m^2; 5.Patients classified as ASA class I–II, indicating no significant underlying diseases; 6.Patients have no visual, auditory, language, or communication impairments.
Exclusion criteria
Exclusion criteria: 1.Anesthesiologists with underlying diseases affecting heart rate variability (HRV) within the past 3 months (e.g., severe arrhythmia, hypertension, other cardiovascular diseases, metabolic diseases, neurological diseases, and others); 2.Anesthesiologists who have used drugs affecting HRV within the past 2 weeks [9] (e.g., cardiovascular drugs, antidepressants, etc.); 3.Anesthesiologists who are long-term smokers, alcohol abusers, or caffeine-dependent individuals (daily intake exceeding 300 mg caffeine); 4.Anesthesiologists with sleep disorders in the past month (e.g., insomnia, daily sleep less than 6 hours); 5.Patients who refuse to continue participation in the study; 6.Patients with allergies to anesthetic drugs; 7.Patients with a history of respiratory system diseases; 8.Patients with uncontrolled clinically significant liver, kidney, hematological, neurological, or metabolic system diseases, as judged by the investigator to be unsuitable for participation; 9.Patients who require rescue or general anesthesia with intubation during gastroscopy; 10.Patients with difficult airways; 11.Pregnant or lactating women; 12.Any other participants deemed unsuitable for the study by the investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Root Mean Square of Successive Differences; | — |
Secondary
| Measure | Time frame |
|---|---|
| Standard Deviation of NN interyals;Standard Deviation of Average NN intervals;Standard Deviation of Successive Differences;Percentage of successive NN intervals that differ by more than 50 ms;Triangular Index of NN intervals;High Frequency power;Low Frequency power;Very Low Frequency power;Ultra Low Frequency power;LF to HF Ratio; | — |
Countries
China
Contacts
Public ContactCui Zhifeng
Tacheng Prefecture People's Hospital of Ili Kazakh Autonomous Prefecture
Outcome results
None listed