Depression
Conditions
Interventions
Gold Standard:The diagnostic criteria are based on the 10th edition of the International Classification of Diseases (ICD-10) and the Manual of Diagnostics and Statistics of Mental Disorders (DSM-5) a
Index test:The diagnostic test evaluated in this study is "Ten Types of Depression-Related Metabolite Determination Kits (Liquid Chromatography-Tandem Mass Spectrometry)" combined with "Depression Aux
Sponsors
CUHK Hospital Affiliated to Southeast University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Subjects fully understand the trial's purpose, nature, methodology, and potential adverse reactions, voluntarily participate in the trial, and sign an informed consent form; 2. Subjects are aged >=18 and <= 60 years, with no gender restrictions; 3. Subjects meeting one of the following criteria: (1) Subjects diagnosed with depression according to the International Classification of Diseases, 10th Revision (ICD-10) criteria; (2) Non-depressed subjects who have been excluded from a diagnosis of depression based on ICD-10 diagnostic criteria.
Exclusion criteria
Exclusion criteria: 1. Depression subjects have improved to the consolidation or maintenance period after treatment; 2.The subject was diagnosed with bipolar disorder or schizophrenia; 3.The subjects suffered from other mental diseases; 4.Oral or injecting hormone treatment in the last week; 5. People with a history of metabolic diseases such as diabetes, abnormal thyroidism, hyperuricemia, gout, etc. in the past year; 6. The patient has serious neurological diseases, brain trauma, cardiovascular and cerebrovascular diseases, liver diseases, kidney diseases and other major somatic diseases; 7. Pregnant woman or breastfeeding; 8. Those who have undergone surgery within 3 months before screening (except outpatient surgery); 9. The researchers believe that there are samples of other factors that are not suitable to participate in this test.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sensitivity;specificity;Positive/negative predictive value; | — |
Countries
China
Contacts
Public ContactYuan Yonggui
CUHK Hospital Affiliated to Southeast University
Outcome results
None listed