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Study on the Efficacy and Safety of Remimazolam Besylate Combined with Alfentanil in Elderly Patients Undergoing Flexible Bronchoscopy

Study on the Efficacy and Safety of Remimazolam Besylate Combined with Alfentanil in Elderly Patients Undergoing Flexible Bronchoscopy

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500112287
Enrollment
Unknown
Registered
2025-11-12
Start date
2025-12-01
Completion date
Unknown
Last updated
2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None

Interventions

Control Group:Propofol

Sponsors

Inner Mongolia Autonomous Region People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1.Aged >= 65 years and < 80 years; 2.Body Mass Index (BMI) ranging from 18 to 30 kg/m², with American Society of Anesthesiologists (ASA) Physical Status Classification of Grade II-III; 3.Scheduled to undergo painless fiberoptic bronchoscopy with biopsy; 4.Voluntarily participate in this study and sign the informed consent form; 5.Complete clinical data available; 6.Expected duration of fiberoptic bronchoscopy with biopsy < 30 minutes.

Exclusion criteria

Exclusion criteria: 1.History of myocardial infarction or severe arrhythmia; 2.Severe hepatic or renal insufficiency; 3.Previous history of abnormal recovery from surgery or anesthesia; 4.Administration of sedatives or analgesics within 24 hours prior to surgery; 5.Patients with suspected difficult airway; 6.Allergy to study-related drugs or presence of contraindications to such drugs; 7.Inability to communicate normally.

Design outcomes

Primary

MeasureTime frame
Intraoperative Hypoxia Incidence Rate;

Secondary

MeasureTime frame
Success rate of sedation;Hemodynamic levels at different time points;The number of patients requiring airway manipulation during surgery;The number of times the examination needs to be paused due to hypoxemia during surgery;Anesthesia induction time;Endoscopy time ;Recovery time;Satisfaction scores of patients and endoscopists;Intraoperative and postoperative adverse reactions;

Countries

China

Contacts

Public ContactWuu Yun-gerile

Inner Mongolia Autonomous Region People's Hospital

58847727@qq.com+86 180 4719 2710

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026