None
Conditions
Interventions
Experimental Group:Phenylephrine is administered based on the real-time heart rate
Control group:Phenylephrine is administered based on systolic blood pressure
Sponsors
Obstetrics & Gynecology Hospital of Fudan University
Eligibility
Sex/Gender
Female
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Recruit full-term pregnant women over 18 years old who plan to undergo elective cesarean section.
Exclusion criteria
Exclusion criteria: 1. ASA>=?, 2. Body mass index >40Kg/m2, 3. Pre-existing or gestational hypertension, 4. Known fetal abnormalities or intrauterine growth restriction, 5. Any medical contraindications to cardiovascular and cerebrovascular diseases, thrombocytopenia, coagulopathy, combined spinal and dural anesthesia, 6. Known to be allergic to phenylephrine, 7. Inability or refusal to give informed consent. 8 Patients were excluded from subsequent analyses if combined spinal-epidural anesthesia (CSE) was not successfully established, epidural medication was required before delivery, or severe chills made noninvasive blood pressure monitoring unreliable.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of hypotension in parturients;Umbilical cord blood PH; | — |
Secondary
| Measure | Time frame |
|---|---|
| The incidence and severity of hypertension and other adverse hemodynamic events;The satisfaction of postpartum women;The Apgar score of the newborn;The situation of newborns being admitted to the NICU;The BE value of umbilical cord blood; | — |
Countries
China
Contacts
Public ContactWu Han
Obstetrics & Gynecology Hospital of Fudan University
Outcome results
None listed