Pain after total knee arthroplasty
Conditions
Interventions
Expermimental group:bupivacaine liposome mixture with bupivacaine
Sponsors
Tongji Hospital, Tongji Medical College ,Huazhong University of Science and Technology
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.Patients undergoing unilateral knee arthroplasty, ASA physical status I-III;
Exclusion criteria
Exclusion criteria: 1.Bilateral knee joint surgery; 2.Previous history of knee trauma or surgery; 3.Allergic to amide anesthetics; 4.a confirmed or highly suspected infection at the surgical site; 5.Failed to receive spinal anesthesia; 6.weight less than 60 kilograms; 7.Pregnancy or lactation; 8.Patients with opioid dependence;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Opioid consumption 72 hours after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| The total dosage of the rescue analgesic;Opioid-related adverse events and postoperative complications at all specified time points;NRS scores at rest and during movement within 24, 48 and 72 hours postoperatively;The initial administration time of the rescue analgesic;The patient's functional recovery status at each time point;Length of Stay; | — |
Countries
China
Contacts
Public ContactMei Wei
Tongji Hospital, Tongji Medical College ,Huazhong University of Science and Technology
Outcome results
None listed