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Efficacy and Safety of tegileridine combined with paravertebral block for postoperative pain management in gastric cancer patients

Efficacy and Safety of tegileridine combined with paravertebral block for postoperative pain management in gastric cancer patients

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500112238
Enrollment
Unknown
Registered
2025-11-11
Start date
2025-12-01
Completion date
Unknown
Last updated
2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain management

Interventions

A:Tegileridine for analgesic therapy after surgery
B:Sufentanil for analgesic therapy after surgery

Sponsors

Fujian Medical University Union Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: (1)Patients who are scheduled to undergo open or laparoscopic radical gastrectomy for gastric cancer. (2) Age: 18 to 65 years old. (3) ASA classification I-III. (4) Voluntarily sign the informed consent form.

Exclusion criteria

Exclusion criteria: (1) There are contraindications for nerve block (such as infection at the puncture site). (2) There are communication barriers and they are unable to cooperate with the research. (3) Body mass index (BMI) 30 kg/m^2. (4) Preoperative examination indicated that the tumor had distant metastasis. (5) There is a history of chronic pain or chronic opioid use (daily opioid use for >= 3 months or morphine >= 60 mg/d and use for >= 1 month). (6) There are contraindications for the use of the relevant drugs in the research. (7) Participated in other clinical trials within the past three months

Design outcomes

Primary

MeasureTime frame
SPID24;SPID48;

Secondary

MeasureTime frame
SPID;the time of the first postoperative remedial analgesia;Cumulative dosage and frequency of remedial analgesic drugs within 0 to 48 hours;Incidence of chronic pain;

Countries

China

Contacts

Public ContactXianfeng Weng

Fujian Medical University Union Hospital

wxffz@sina.com+86 133 6591 0675

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026