Skip to content

Effect of Liposomal Bupivacaine Combined with Ultrasound-Guided Fascia Iliaca Compartment Block on Postoperative Analgesia and Enhanced Recovery in Elderly Patients Undergoing PFNA Internal Fixation: A Randomized Double-Blind Controlled Trial

Effect of Liposomal Bupivacaine Combined with Ultrasound-Guided Fascia Iliaca Compartment Block on Postoperative Analgesia and Enhanced Recovery in Elderly Patients Undergoing PFNA Internal Fixation: A Randomized Double-Blind Controlled Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500112234
Enrollment
Unknown
Registered
2025-11-11
Start date
2025-11-12
Completion date
Unknown
Last updated
2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intertrochanteric fracture of the femur

Interventions

Control group :0.3% Ropivacaine Injection 30 mL
Experimental group:10 mL (133 mg) of bupivacaine liposome injection suspension + 20 mL of 0.9% normal saline

Sponsors

people's hospital of wenjiang
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1. From October 2025 to June 2026, visited the Department of Orthopedics at Wenjiang Hospital of Sichuan Provincial People's Hospital; 2. Age: 65 years old or above, 90 years old or below, gender not limited. 3. Admitted to the hospital due to intertrochanteric fracture of the femur and scheduled for PFNA internal fixation. 4.ASA classification grades I to IV. Be capable of understanding and conducting VAS scores, QoR15 scores, and delirium scale scores, etc. 5. Voluntarily sign the informed consent form and be willing to abide by the requirements of the research protocol

Exclusion criteria

Exclusion criteria: 1. Fractures that do not meet the inclusion criteria, such as pathological fractures, pelvic fractures, old fractures, and multiple fractures throughout the body; 2. Patients with a history of diagnosed mental illness or those currently taking psychotropic drugs; 3. The patient does not understand the test method or refuses the test, and is allergic to any drug component; 4. There are contraindications for nerve block (infection at the needle insertion site, coagulation dysfunction, international normalized ratio >1.4, platelet count <80×10^9/L); 5. Anatomical structures cannot be identified or surface positioning points cannot be determined under ultrasound (such as hematoma at the puncture site, femoral artery trauma); 6. Patients with unstable vital signs.

Design outcomes

Primary

MeasureTime frame
Pain evaluation 72 hours after nerve block;

Secondary

MeasureTime frame
Security;

Countries

China

Contacts

Public ContactLiu Chang

Chengdu Wenjiang District People's Hospital

1191556241@qq.com+86 28 8271 5731

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026