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Evaluation of postoperative analgesic effects of liposomal bupivacaine and ropivacaine in Interscalene brachial plexus block: a randomized controlled trial

Evaluation of postoperative analgesic effects of liposomal bupivacaine and ropivacaine in Interscalene brachial plexus block: a randomized controlled trial

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500112232
Enrollment
Unknown
Registered
2025-11-11
Start date
2025-12-01
Completion date
Unknown
Last updated
2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Rotator Cuff Injury

Interventions

Group B:0.5% ropivacaine 12ml
Group A:10 ml of liposomal bupivacaine solution (133mg)+2 ml of 0.9% saline solution

Sponsors

Liaoning Provincial People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. The patient is aged between 18 and 80 years old (including boundary values) 2. Plan to schedule a shoulder arthroscopy surgery. 3. The patient has an American Society of Anesthesiologists (ASA) score of I to II. 4. Normal heart and lung function. 5. Those who voluntarily sign the informed consent form.

Exclusion criteria

Exclusion criteria: Refusal to participate, surgical site infection, existing anatomical abnormalities, history of drug allergies to research drugs, peripheral nerve lesions, musculoskeletal and radial or ulnar nerve lesions, mental disorders, coagulation dysfunction, BMI>35 kg/m^2, Severe lung disease, heart failure, cerebrovascular disease, liver dysfunction, severe renal dysfunction, pregnant or lactating women, long-term use of opioid drugs, and those who have participated in other clinical trials within the past 3 months.

Design outcomes

Primary

MeasureTime frame
Patient NRS pain score;

Secondary

MeasureTime frame
Duration of sensory;Duration of motor block;Demand for analgesics within 72 hours after operation;The incidence of postoperative nausea and vomiting;Systolic pressure;Diastolic pressure;Mean arterial pressure;Heart rate;Oxygen saturation;BIS;

Countries

China

Contacts

Public ContactChangming Wang

Liaoning Provincial People's Hospital

teamwangcm@163.com+86 177 0248 6100

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026