Cancer-related cognitive impairment
Conditions
Interventions
Combined Treatment Group:Participants will receive one session of cognitive training targeting different cognitive domains and undergo biofeedback therapy once daily.
Biofeedback Therapy Group:Participants will receive biofeedback therapy once daily.
Sponsors
Fudan University Shanghai Cancer Center
Eligibility
Sex/Gender
Female
Age
27 Years to 67 Years
Inclusion criteria
Inclusion criteria: (1) Female patients aged 18 to 70 years. (2) Pathologically confirmed invasive breast carcinoma. (3) Have undergone breast-conserving surgery and are eligible for adjuvant radiotherapy. (4) Have completed at least 4 to 6 cycles of standard neoadjuvant and/or adjuvant chemotherapy containing taxanes and/or anthracyclines. (5) Have signed the informed consent form.
Exclusion criteria
Exclusion criteria: (1) Patients with a history of malignancy or concurrent malignant tumors. (2) Patients who have previously received radiotherapy to the breast or chest area. (3) Pregnant or breastfeeding women. (4) Patients with a prior confirmed diagnosis of bipolar disorder, schizophrenia, schizoaffective disorder, or other psychiatric disorders secondary to medical conditions. (5) Illiterate patients, color-blind individuals, or those with severe impairments in hearing, speech, reading, or writing. (6) Patients who are unable to comply with follow-up requirements.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Eye-movement Assessment;Niacin Skin Flush Test;Perceived Deficits Questionnaire–5;Auditory Verbal Learning Test – Delayed Recall;Trail Making Test-A;Trail Making Test-B;Digit Span Test;Coding Test; | — |
Secondary
| Measure | Time frame |
|---|---|
| EORTC-QLQ-C30;EORTC-QLQ-BR23;Generalized Anxiety Disorder-7;Patient Health Questionnaire-9;Patient Health Questionnaire-15;Pittsburgh Sleep Quality Index;Mood Disorder Questionnaire;Eysenck Personality Questionnaire;Visual Analogue Scale; | — |
Countries
China
Contacts
Public ContactFeng Wei
Fudan University Shanghai Cancer Center
Outcome results
None listed