Schizophrenia
Conditions
Interventions
Sponsors
The Affiliated Brain Hospital of Nanjing Medical University
Eligibility
Sex/Gender
All
Age
20 Years to 80 Years
Inclusion criteria
Inclusion criteria: Inclusion Criteria for the Schizophrenia Group: 1.Meet the diagnostic criteria for schizophrenia according to the Diagnostic and Statistical Manual of Mental Disorders (DSM-5); 2.Aged 20–80 years; 3.Of Han Chinese ethnicity; 4.With an educational level of junior high school or above; 5.Willing to participate in the study. Inclusion Criteria for the Healthy Control Group: 1.No personal or first-degree family history of psychiatric disorders such as schizophrenia, mood disorders, personality disorders, or intellectual disability; 2.No severe physical diseases, including organic brain diseases or endocrine disorders; 3.No history of alcohol/drug dependence or abuse; 4.Ability to comprehend the study content and willingness to participate.
Exclusion criteria
Exclusion criteria: 1.Comorbid presence of other psychiatric disorders; 2.Pregnancy or lactation; 3.Diagnosis of terminal illnesses, including renal failure, heart failure, cancer, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Transcriptomics;Proteomics;Metabolomics;Extracellular vesicle transcriptomics;Extracellular vesicle metabolomics;Extracellular vesicle proteomics;DNA methylation;Telomere length;Senescence-associated secretory phenotype (SASP);Retinal arteriovenous ratio;Ankle–brachial index;Carotid intima–media thickness;Brief Psychiatric Rating Scale;Scale for Assessment of Positive Symptoms;Scale for Assessment of Negative Symptoms;Schedule for the Deficit Syndrome;Snaith-Hamilton Pleasure Scale;Temporal Experience of Pleasure Scale ;Childhood Trauma Questionnaire;International Physical Activity Questionnaire;Pittsburgh Sleep Quality Index;Social Functioning Deficits Scale; | — |
Countries
China
Contacts
Public ContactXiangrong Zhang
The Affiliated Brain Hospital of Nanjing Medical University
Outcome results
None listed