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Effects and Brain Network Mechanisms of Central Repeated Transcranial Magnetic Stimulation Synchronized with Peripheral Action Observation Visual Input on Functional Recovery after Stroke

"Central-Peripheral-Central" Repetitive Functional Magnetic Neuromodulation Strategy Based on Neural Networks for Improving Dysfunction after Central Nervous System Injury

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500112167
Enrollment
Unknown
Registered
2025-11-11
Start date
2025-12-01
Completion date
Unknown
Last updated
2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Upper limb motor dysfunction after stroke

Interventions

active rTMS+active AOT:Active rTMS stimulation combined with active AOT stimulation
placebo rTMS+active AOT:rTMS placebo stimulation combined with active AOT stimulation
active rTMS+placebo AOT:Active rTMS stimulation combined with AOT placebo stimulation
Placebo rTMS+placebo AOT:rTMS placebo stimulation combined with AOT placebo stimulation

Sponsors

The First Affiliated Hospital of Soochow University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1.Age 18-80 years; 2.Right-handed; 3.Signed informed consent form.

Exclusion criteria

Exclusion criteria: 1.Contraindications to functional magnetic stimulation, such as metal implants near the stimulation site; 2.Pregnancy, recent history of myocardial infarction, severe cardiac dysfunction, severe dysfunction of major organs, uncontrolled hypertension, or comorbid epilepsy; 3.Contraindications to magnetic resonance imaging (MRI); 4.Other conditions that may compromise the ability to cooperate with treatment and evaluation.

Design outcomes

Primary

MeasureTime frame
Upper limb Fugl-Meyer scale score;

Secondary

MeasureTime frame
Modified Barthel Index;Neurophysiological indicators;Action Research Arm Test(ARAT);

Countries

China

Contacts

Public ContactZhu Hongjun

The First Affiliated Hospital of Soochow University

hjzhu1977@163.com+86 512 67781081

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026