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Effect of different doses of oxycodone on the minimal alveolar concentration of desflurane under electrosurgical stimulation during upper gastrointestinal endoscopic submucosal dissection

Effect of different doses of oxycodone on the minimal alveolar concentration of desflurane under electrosurgical stimulation during upper gastrointestinal endoscopic submucosal dissection

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500112159
Enrollment
Unknown
Registered
2025-11-11
Start date
2025-11-20
Completion date
Unknown
Last updated
2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

early gastric cancer

Interventions

C group:Intravenous push 10ml of normal saline before anesthesia induction
O1 group:Intravenous push 10ml of 0.1 mg/kg oxycodone before anesthesia induction
O2 group:Intravenous push 10ml of 0.15 mg/kg oxycodone before anesthesia induction
O3 group:Intravenous push 10ml of 0.2 mg/kg oxycodone before anesthesia induction

Sponsors

No. 1 Maoyuan South Road, Shunqing District, Nanchong City, Sichuan Province
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Patients with ESD in the upper gastrointestinal tract; 2. ASA classification: Grade II-III; 3. Age range: 18-65 years old.

Exclusion criteria

Exclusion criteria: Patients who refuse to sign the informed consent form for the trial, have recently taken analgesics or sedatives, have a history of chronic pain, mental disorders, alcohol abuse or drug abuse, are allergic to oxycodone and desflurane, have a family history of malignant hyperthermia, are contraindicated to succinylcholine, or have a body mass index (BMI) greater than 30 or less than 18 kg/m^2.

Design outcomes

Primary

MeasureTime frame
Minimum alveolar effective concentration of desflurane;

Secondary

MeasureTime frame
Wake-up time;Extubation time;Visual analogue pain scale;Ramsay Sedation score;

Countries

China

Contacts

Public ContactKai Luo

Affiliated Hospital of North Sichuan Medical College?

1657178268@qq.com+86 130 8637 0759

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026