Insomnia, Depression
Conditions
Interventions
Exposure group:None
Control group:None
Sponsors
Shanghai Fourth People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-75 years; 2. Received treatment for sleep problems at the Department of Sleep Medicine, Shanghai Fourth People's Hospital between February 2022 and February 2025. 3. Diagnosed with insomnia disorder according to ICSD-3 criteria. 4. Diagnosed with major depressive disorder according to DSM-5 criteria. 5. Insomnia Severity Index (ISI) score >7 and Hospital Anxiety and Depression Scale-Depression (HADS-D) subscore >10. 6. Underwent treatment with either combined esketamine and CBT-I or CBT-I alone. 7. Availability of complete baseline data of interest.
Exclusion criteria
Exclusion criteria: 1. Diagnosis of schizophrenia, bipolar disorder, recurrent panic attacks, or active suicidality. 2. Presence of dysarthria, hearing impairment, or cognitive dysfunction. 3. Other types of sleep disorders, such as sleep apnea, restless legs syndrome, or sleep-related movement disorders. 4. Receipt of other interventional treatments.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Adherence to Behavioral Strategies; | — |
Secondary
| Measure | Time frame |
|---|---|
| Bedtime variability;Wake-up time variability;CBT-I Completion Rate;Insomnia Severity Index;Response rate and remission rate;Hospital Anxiety and Depression Scale;Equivalent dose of benzodiazepines; | — |
Countries
China
Contacts
Public ContactQifang Li
Shanghai Fourth People's Hospital
Outcome results
None listed