Mild cognitive impairment
Conditions
Interventions
Group 1:The Baduanjin training lasts for 12 weeks, with 30 minutes each time, three times a week
Group 2:Traditional pen and paper cognitive training, 30 minutes each time, three times a week, for a period of 12 weeks
Group 3:A sequential combined cognitive training of Baduanjin, 60 minutes each time, three times a week, for a period of 12 weeks
Group 1 (Part Two of the study):Five patients who agreed to undergo fNIRS measurement were randomly selected from the group in the first part of the study.
Group 2 (Part Two of the study):Five patients who agreed to undergo fNIRS measurement were randomly selected from the group in the first part of the study.
Group 3 (Part Two of the study):A sequential combined cognitive training of Baduanjin, 60 minutes each time, three times a week, for a period of 12 weeks(Five patients who agreed to undergo fNIRS meas
Sponsors
Shanghai Yangpu Central Hospital
Eligibility
Sex/Gender
All
Age
60 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age >=60 years old; 2. According to Petersen's diagnostic criteria and the diagnostic criteria for MCI in the 2018 Chinese Guidelines for the Diagnosis and Treatment of Dementia and Cognitive Impairment, having MCI includes: 1) Cognitive impairment is reported by patients or informed parties, or discovered by experienced clinicians; 2) Objective evidence of impairment in one or more cognitive functional domains (Beijing version MoCA score >=18, <=25 points); 3) Complex instrumental daily living abilities may be slightly impaired, but the ability to maintain independent daily living (muscle strength level 3 or above, capable of walking independently and safely for 10 meters or more without external force or assistive devices) can be maintained. 4) The diagnosis of dementia has not yet been reached; 3. The condition is stable, consciousness is clear, and vital signs are stable; 4. Informed consent and voluntary participation;
Exclusion criteria
Exclusion criteria: 1. Central nervous system diseases such as dementia, acute brain injury, Parkinson's disease, and mental disorders; 2. It has been confirmed by previous medical records, clinical doctors or family members that the individual was using drugs for cognitive impairment before the onset of the disease; 3. Those with severe speech, vision, hearing impairments and other conditions that affect cognitive tests; 4. There are unstable or severe diseases of the heart, lungs, liver, kidneys, hematopoietic system, and serious diseases with poor prognosis such as informed malignant tumors; 5. Those who have exercised regularly within half a year (moderate or higher intensity, >=30 minutes per day, >=3 days per week); 6. Those who are currently participating in clinical trials of cognitive intervention in other specialties and will affect the outcome evaluation of this study; 7. Illiterate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Overall cognitive function;The change value of oxygenated hemoglobin (oxy-Hb) concentration in brain regions; | — |
Secondary
| Measure | Time frame |
|---|---|
| Memory;Language function;Pay attention to the processing speed;Balance function;Quality of daily life; | — |
Countries
China
Contacts
Public ContactXuemin Li
Shanghai Yangpu Central Hospital
Outcome results
None listed