Individuals experiencing anxiety or depression during an overseas assignment
Conditions
Interventions
Test group:After a four-week intervention with regular noodles, there was a four-week washout period, followed by a four-week intervention with functional oligosaccharide noodles.
Sponsors
Shanghai Changzheng Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: 1. Conduct consecutive sea-going missions. The duration of the recent sea mission is more than 14 days, and the rest and recovery time before enrollment does not exceed 3 days. 2. Healthy individuals aged 18 years and above. 3. Able to comply with the requirements of the research protocol and the assessment window period. 4. Take the product as per the instructions. 5. Willing to collect, store and deliver fecal samples according to the instructions. 6. During the study period, the subjects can use the nutrition mini-program on their smartphones to record a 24-hour dietary diary for 3 days. 7. Sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Known/Existing gastrointestinal diseases such as chronic colitis, history of gastrointestinal surgery, or diseases diagnosed by doctors that may interfere with the study; 2. Known/Existing allergies to seafood, seafood products, wheat bran, or to other product components; 3. Individuals with a daily intake of more than 30g of dietary fiber; 4. Those who have taken glucocorticoids, antibiotics, prebiotics, probiotics, vitamin supplements, and any other drugs that may affect microbiome analysis within 4 weeks before enrollment; 5. Individuals with severe physical diseases and brain organic diseases; 6. Individuals with alcohol, drug, or neuroanesthetic drug dependence; 7. Subjects with special diets, including but not limited to vegan diet, ketogenic diet, low-fiber diet, thickening diet, etc. 8. Those judged by the investigators not to be able to comply with the protocol (those who cannot stay on the surface vessel for a full 8 weeks after enrollment); 9. Participating in any other study that may affect the results simultaneously or within 2 weeks before enrollment; 10. Having constipation/diarrhea within one month before enrollment; 11. Having received functional oligosaccharide intervention (such as shell oligosaccharides, low-molecular-weight xylose, low-molecular-weight fructose) within half a year before enrollment; 12. Pregnant or lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| self-rating anxiety scale;Self-rating depression scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| cortisol;Intestinal flora;Metabolomic characteristics;Testosterone; | — |
Countries
China
Contacts
Public ContactLi Juan
Shanghai Changzheng Hospital
Outcome results
None listed