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Effect of popliteal sciatic nerve block with bupivacaine liposomes on postoperative pain and postoperative recovery quality in patients undergoing foot orthopedic surgery

The effect of liposomal bupivacaine peripheral nerve block on postoperative pain and recovery quality in patients

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500112093
Enrollment
Unknown
Registered
2025-11-10
Start date
2025-11-18
Completion date
Unknown
Last updated
2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Foot deformity

Interventions

Group B:Popliteal sciatic nerve block (bupivacaine liposome)
Group L:Popliteal sciatic nerve block (ropivacaine)

Sponsors

Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1.Age 18-60 years old, gender is not limited. 2. Patients who scheduled for foot orthosis. 3. ASA Grade I to II. 4. Sign informed consent.

Exclusion criteria

Exclusion criteria: 1. A long history of taking analgesics (such as opioids, acetaminophen, or NSaids); 2. History of abnormal coagulation; 3. Allergic to the drug to be used; 4. Skin infection at the puncture site of nerve block. 5. Language and mental disorders and can not complete the pain score and postoperative recovery quality score.

Design outcomes

Primary

MeasureTime frame
15-item Quality of Recovery Rating Scale (QoR-15) Score;

Secondary

MeasureTime frame
Pain score at rest, movement;Analgesic pump usage within 24 hours after surgery;Dosage of oral remedial analgesics;Myodynamia;Athens Insomnia Scale Score;Hospital Anxiety and Depression Scale Score;Satisfaction of patients;Nausea and vomiting;Pruritus;Respiratory depression;Hematoma or infection at the puncture site;Synesthesia;Intraoperative hypotension;Intraoperative bradycardia;Operation duration;Anesthesia duration;Duration of analgesia;

Countries

China

Contacts

Public ContactChen Chunmei

Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College

chunmeichen2008@163.com+86 186 1161 2186

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026