catheter related bladder discomfort
Conditions
Interventions
Group A: Vitamin C + Dexmedetomidine Group:During anaesthetic induction, administer a loading dose of dexmedetomidine at 1 µg/kg via infusion pump, followed by a continuous infusion of 0.4 µg/kg/h. Co
Group B: Dexmedetomidine Group:During anaesthetic induction, administer a loading dose of 1 µg/kg dexmedetomidine via infusion pump, followed by a continuous infusion of 0.4 µg/kg/h. Concurrently, adm
Group C: Control Group :During induction, administer normal saline via infusion pump at the volume and method calculated for the dexmedetomidine group. Cease infusion 30 minutes prior to the conclusio
Sponsors
The First People’s Hospital of Shuangliu District, Chengdu
Eligibility
Sex/Gender
Male
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Male patients scheduled for elective non-urological surgery under general anesthesia; 2. ASA physical status class I-III; 3. Age 18–75 years; 4. No communication barriers and able to understand the study protocol; 5. Voluntarily participate in the study and provide written informed consent.
Exclusion criteria
Exclusion criteria: 1. Preoperative presence of prostatic disease, urethral stricture, urethral injury, or other urological conditions requiring treatment; 2. History of urological surgery or planned urological surgery in this admission; 3. Self-reported preoperative symptoms of urinary frequency, urgency, or dysuria; 4. Communication or cognitive impairment preventing adequate understanding or cooperation; 5. Severe cardiac, pulmonary, hepatic, or renal insufficiency; 6. Inability to insert a urinary catheter; 7. History of prior urinary catheterization; 8. Allergy to dexmedetomidine or vitamin C.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Moderate to severe CRBD rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Agitation Score;Ramsay Sedation Scale;Incidence of CRBD;The severity of CRBD;Pain Rating: Digital Rating Scale (NRS);Number of button presses for patient-controlled intravenous analgesia within 24 hours post-surgery;Adverse reactions within 24 hours postoperatively (nausea, vomiting, drowsiness, dizziness, bradycardia, hypotension);Satisfaction rating;Amount of flurbiprofen axetil used; | — |
Countries
China
Contacts
Public ContactMa Fengting
The First People’s Hospital of Shuangliu District, Chengdu
Outcome results
None listed