Transplanted Kidney Diseases
Conditions
Interventions
Index test:Ultrasound ultra resolution microscopy imaging
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. First-time recipients of allogeneic renal transplants, including living or deceased donors; 2. Age >=18 years; 3. End-to-side anastomosis of the donor renal artery to the external or internal iliac artery; 4. Within 7 days post-operation.
Exclusion criteria
Exclusion criteria: 1. Combined multi-organ transplantation; 2. Second or subsequent renal transplantation, dual kidney transplantation (mostly recipients of pediatric donor kidneys); 3. History of malignancy; 4. Severe failure of other organs (e.g., heart, liver, lungs, etc.); 5. Contraindications related to ultrasound contrast agents; 6. Lactation or pregnancy; 7. Hydronephrosis of the transplanted kidney >=2 cm, moderate to large peritransplant fluid collection [maximum depth of fluid >=2 cm, including complications such as urinary tract obstruction, urinoma (urine leakage, first 2 weeks post-operation), lymphocele (4-8 weeks post-operation), perirenal infection, etc.]; 8. Inability to cooperate, unsatisfactory image acquisition, or missing clinical data.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Microvascular imaging-related indicators (URM density, URM Curvature, URM Complexity Level, Density Fit, Density Analysis, URM Location Velocity, Velocity Analysis, Perfusion Index, Density Velocity Analysis);Viscoelastic ultrasound measurement values;Glomerulus Number;Glomerulus Density;Repeat dialysis rate;Predictive performance; | — |
Secondary
| Measure | Time frame |
|---|---|
| Grayscale ultrasound (size, echo intensity, renal cortical thickness);Spectral Doppler ultrasound (PSV, EDV, RI, and PI); | — |
Countries
China
Contacts
Public ContactJiaojiao Zhou
West China Hospital, Sichuan University
Outcome results
None listed