Postoperative pain
Conditions
Interventions
Paravertebral Block+Liposomal Bupivacaine (PVB+LB):After anesthesia induction, the patient was placed in the lateral position. Under aseptic conditions, a linear ultrasound probe was placed in the par
Paravertebral Block+Ropivacaine (PVB+R):After anesthesia induction, the patient was positioned laterally. Under ultrasound guidance and sterile preparation, a linear probe was placed in the parasagitt
after pleural movement was seen with a small test dose, the remaining local anesthetic was injected. Each level was injected with 5mL of 0.5% ropivacaine, totaling 20mL
Intercostal Nerve Block+Liposomal Bupivacaine (INB+LB):After anesthesia induction and lateral positioning, the surgeon created a 3 cm incision for thoracoscopy. Under thoracoscopic visualization, a 22
Intercostal Nerve Block+Ropivacaine (INB+R):Aft
Sponsors
Tongji Hospital affiliated to Tongji Medical College of Huazhong University of Science and Technology
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Patients aged between 18 and 75 years, regardless of gender; 2. Scheduled for elective thoracoscopic pulmonary surgery in the Department of Thoracic Surgery; 3. Able to cooperate with interviews and complete scale assessments; 4. Classified as American Society of Anesthesiologists (ASA) physical status I–III; 5. Provided written informed consent.
Exclusion criteria
Exclusion criteria: 1. History of ipsilateral breast surgery; 2. Allergic to local anesthetics or have contraindications; 3. Contraindications to paravertebral or intercostal nerve block puncture; 4. Body mass index (BMI) > 35 kg/m^2; 5. Suffering from mental disorders, intellectual disabilities, epilepsy, or similar conditions; 6. Severe heart or lung disorders and liver or kidney dysfunction; 7. History of chronic chest pain; 8. History of drug abuse, substance abuse, or alcoholism; 9. Pregnant or breastfeeding women; 10. Participation in other clinical studies recently.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Brief Pain Inventory (BPI)–Worst pain intensity within 24 hours after surgery;Neuropathic pain (DN4); | — |
Secondary
| Measure | Time frame |
|---|---|
| BPI pain scores at other time points 3 days postoperatively;Consumption of analgesic drugs;Duration of blockade;Patient satisfaction with pain relief;Perioperative complications;Rescue analgesic doses;length of hospital stay;Chest tube removal time;Time to first ambulation;Symptom burden (MDASI-LC) Score;Quality of life (EQ-5D-5L) Score; | — |
Countries
China
Contacts
Public ContactFeng Gao
Tongji Hospital affiliated to Tongji Medical College of Huazhong University of Science and Technology, Qiaokou District, Wuhan City, Hubei Province
Outcome results
None listed