Depression
Conditions
Interventions
Experimental group:under the guidance of a psychologist, the patient received olanzapine 5 mg/qn+ paroxetine hydrochloride 20 mg/qd orally from the day of admission and olanzapine 5 mg and celecoxib 0
Control group:patients did not receive any oral drugs at admission and received 0.2 g of celecoxib orally the night after surgery and 0.2 g/bid of celecoxib from the first day after surgery to dischar
Sponsors
Affiliated Hospital of Jining Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Aged between 18 and 70 years old, 2. Routine blood test, blood coagulation test, liver and kidney function, blood lipid and blood glucose, six and three hepatitis antibodies, electrocardiogram and chest X-ray were all within the normal range. 3. No history of mental illness, normal communication and understanding ability.
Exclusion criteria
Exclusion criteria: 1. Preoperative history of other comorbidities and other systemic diseases or surgery, including Crohn's disease; 2. Pregnant or lactating women; 3. Hemorrhoids complicated with complex anal fistula or perianal abscess; 4. Male prostate disease and other lesions with increased abdominal pressure; 5. Repeated hemorrhoids resection and recurrent hemorrhoids; 6. Patients who had taken antidepressant drugs before treatment; 7. Patients with other types of mental disorders; 8, cardiovascular and cerebrovascular, liver and kidney function, lung function, hematopoietic function, nerve function and other important organs of the body serious lesions; 9. Patients who had taken medication for chronic pain for a long time.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual analog scale (VAS) score;Self-rating anxiety scale (SAS) score;Self-rating depression scale (SDS) score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Analgesic effect;Sleep quality;Urination condition; | — |
Countries
China
Contacts
Public ContactShubo Gao
Affiliated Hospital of Jining Medical University
Outcome results
None listed