coronary heart disease,Ischemic Mitral Regurgitation
Conditions
Interventions
Case series:none
Sponsors
Fuwai Hospital, Chinese Academy of Medical Sciences,
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age >=18 years, secondary mitral regurgitation discovered during outpatient visit or hospitalization; 2. Have definite coronary heart disease; 3. Cardiac ultrasound: consistent with mitral regurgitation caused by myocardial ischemia or myocardial infarction: Segmental wall motion abnormality or Mitral regurgitation is consistent with Carpentier type IIIb (eccentric regurgitation); 4. Cardiac ultrasound prompts: moderate or above ischemic mitral regurgitation.
Exclusion criteria
Exclusion criteria: 1. Patients within the past year or currently participating in other clinical studies; 2. Primary mitral regurgitation (such as mitral valve prolapse, perforation, chordae tendineae rupture, etc.); 3. Dilated cardiomyopathy, hypertrophic cardiomyopathy and other diseases; 4. Moderate and above aortic stenosis/regurgitation, mitral stenosis, tricuspid stenosis, etc.; 5. Patients who have undergone cardiac valve intervention/surgery
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Composite endpoint of heart failure hospitalization and all-cause death; | — |
Secondary
| Measure | Time frame |
|---|---|
| Change in mitral regurgitation severity;All-cause mortality;Hospitalization for heart failure; | — |
Countries
China
Contacts
Public ContactErli Zhang
Fuwai Hospital, National Center for Cardiovascular Diseases Chinese Academy of Medical Sciences and Peking Union Medical College
Outcome results
None listed