Neonatal sepsis
Conditions
Interventions
Neonatal sepsis:None
Sponsors
Affiliated Hospital of Jining Medical University
Eligibility
Sex/Gender
All
Age
No minimum to 1 Years
Inclusion criteria
Inclusion criteria: The study population consists of neonates hospitalized in the NICUs of various centers who meet the suspected, clinical, or definitive diagnostic criteria for neonatal sepsis as outlined in the Expert Consensus on the Diagnosis and Treatment of Neonatal Sepsis (2024). 1. Suspected Diagnosis of Neonatal Sepsis For EOS: Clinical abnormalities within 72 h after birth. 2. Clinical Diagnosis of Neonatal Sepsis: Presence of clinical abnormalities, plus fulfillment of any one of the following criteria: At least two positive results from non-specific blood tests; Cerebrospinal fluid (CSF) findings consistent with purulent meningitis; Detection of pathogen DNA in blood or CSF. 3. Definitive Diagnosis of Neonatal Sepsis: Presence of clinical manifestations, plus a positive blood culture or culture of CSF (or other sterile body fluid).
Exclusion criteria
Exclusion criteria: 1. Neonates with inherited metabolic diseases or congenital malformations; 2. Neonates with severe asphyxia at birth, persistent pulmonary hypertension of the newborn, severe intracranial hemorrhage, or other such diseases; 3. Respiratory or circulatory failure caused by non-infectious factors; 4. Guardians who disagree with the neonate's participation in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Septic shock;Neurodevelopmental disorders;diagnosed with sepsis; | — |
Secondary
| Measure | Time frame |
|---|---|
| In-hospital mortality;Pyogenic meningitis;Chronic lung disease; | — |
Countries
China
Contacts
Public ContactWang Huabin
Affiliated Hospital of Jining Medical University
Outcome results
None listed