Constipation
Conditions
Interventions
none-Constipation group:None
Sponsors
Zhejiang Hospital
Eligibility
Sex/Gender
All
Age
55 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) Underwent primary unilateral PKA (either TKA or UKA) at Zhejiang Hospital during the study period; (2) Had complete EMR data, including baseline demographic information, perioperative records (e.g., surgical details, medication use), and postoperative outcomes (e.g., defecation frequency, symptom documentation).
Exclusion criteria
Exclusion criteria: (1) They had a history of chronic constipation within 6 months before surgery, defined by the Rome IV criteria (recurrent constipation symptoms for >=3 months, with onset >=6 months before diagnosis) ; (2) They had preexisting severe GI diseases, including intestinal obstruction, inflammatory bowel disease (Crohn’s disease or ulcerative colitis), or GI malignancy (to eliminate preexisting GI dysfunction as a confounder); (3) They developed severe postoperative complications (e.g., prosthetic joint infection, septic shock, acute myocardial infarction, or stroke), as these conditions and their treatments (e.g., vasopressors) independently affect GI motility; (4) They had cognitive impairment (e.g., Alzheimer’s disease, post-stroke cognitive deficit) or psychiatric disorders (e.g., schizophrenia, bipolar disorder) that prevented reliable reporting of defecation symptoms; (5) Merge with end-stage malignant tumors or expected survival of less than 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Generalized Anxiety Disorder-7, GAD-7; | — |
Secondary
| Measure | Time frame |
|---|---|
| Surgical Method ;Anesthesia Method;Whether Rehabilitation Therapy Was Administered;Preoperative Medication Administration; | — |
Countries
China
Contacts
Public ContactYanzhi Ge
Zhejiang Hospital
Outcome results
None listed