Scar prevention/repair
Conditions
Interventions
Open micro irrigation OFM technology:None
Franz diffusion pool method:None
Sponsors
Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Male and female participants aged 18 to 65 years old (including 18 and 65 years old); 2. Accept plastic surgery, during which excess skin tissue must be removed, and the area of normal skin tissue removed in the same region must be >= 100cm^2; 3. Those who are able to communicate well with researchers, fully understand the purpose and requirements of this trial, voluntarily participate in clinical trials, and sign a written informed consent form for biological sample collection.
Exclusion criteria
Exclusion criteria: 1.Open wounds or redness, irritation, or damage to the skin; 2.The skin color is significantly different, which affects the evaluation of the skin (such as the presence of scar tissue exceeding 10% of the excised skin, tattoos, abnormal skin color, texture, etc.); 3. Previous skin diseases, such as atopic dermatitis, psoriasis, vitiligo, or diseases known to change skin appearance or physiological reaction (such as diabetes, porphyria); 4. Referring to the four preoperative examinations of our hospital, syphilis (TP), five hepatitis B, hepatitis C (HCV), and human immunodeficiency virus (HIV), any of which is clinically significant; 5. Before screening, drugs or patches that have an impact on the skin cannot be identified as completely metabolized; 6. The researcher determines that they are not suitable to participate in this clinical study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Maximum permeation rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Analysis of Infiltration Promotion Mechanism; | — |
Countries
China
Contacts
Public ContactYixin Zhang
Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine
Outcome results
None listed