gastroesophageal reflux disease
Conditions
Interventions
Morning-type:None
Middle-type:None
Evening-type:None
Sponsors
The First Affiliated Hospital of Dalian Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Male or female individuals aged 18 years or above 2. Completed gastroscopy, esophageal pressure measurement and 24-hour pH impedance monitoring tests 3. Diagnosed with gastroesophageal reflux disease 4. Normal intelligence quotient, capable of performing basic communication and interaction 5. No significant changes in daily routine within the last 3 months (defined as job changes, cross-time zone travel, night shift to day shift transitions, etc.) 6. Regular use of PPI treatment for 8 weeks 7. Voluntary signing of informed consent form 8. Availability of complete clinical data
Exclusion criteria
Exclusion criteria: 1. Insufficient data 2. Has been using PPI for a long time (> 1 month) or has recently adjusted the dosage of PPI (within the last 1 month) 3. Presence of diseases such as achalasia of the cardia or outflow obstruction. 4. Concurrent diabetes, fever, a history of skin allergies, or allergies occurring during treatment. 5. Concurrent gastrointestinal tumors, severe peptic ulcers, inflammatory bowel disease, and other gastrointestinal diseases, as well as serious chronic diseases or severe systemic diseases such as scleroderma and Sjögren's syndrome. 6. History of abdominal surgery; special patients such as those who are pregnant or breastfeeding. 7. Patients with psychiatric disorders or cognitive impairments who are unable to provide adequate responses. 8. Unable to complete follow-up or refuse to sign the informed consent form.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| sex;age;BMI;GerdQ Scale; | — |
Countries
China
Contacts
Public ContactDuan Zhijun
The First Affiliated Hospital of Dalian Medical University
Outcome results
None listed