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The effect of Tegileridine on postoperative pain in patients undergoing thoracoscopic lung surgery: A single-center, randomized, double-blind, controlled study

The effect of Tegileridine on postoperative pain in patients undergoing thoracoscopic lung surgery: A single-center, randomized, double-blind, controlled study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500112009
Enrollment
Unknown
Registered
2025-11-10
Start date
2025-11-28
Completion date
Unknown
Last updated
2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain

Interventions

Sponsors

The Fourth Hospital of Hebei Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: (1) Age range from 18 to 75 years old; (2) Patients planning to undergo thoracoscopic lung surgery; (3) ASA classification levels I-III; (4) BMI 18~30kg/m^2. (5) Voluntarily participate and sign an informed consent form.

Exclusion criteria

Exclusion criteria: (1) There were already other acute and chronic pains before the surgery; (2) Pregnancy, lactation, or planned pregnancy; (3) There are contraindications to the use of anesthetics, adjunctive analgesics, salvage analgesics, and antiemetic drugs in the study; (4) Long term treatment with opioid drugs or use of any analgesic within 48 hours prior to surgery; (5) Suffering from sleep apnea syndrome; (6) Suffering from mental and neurological disorders, gastrointestinal obstruction, chronic obstructive pulmonary disease or pulmonary heart disease, severe cardiovascular disease, etc; (7) Acute or severe bronchial asthma patients without vital sign monitoring or life resuscitation equipment (8) The researchers believe that participants who are not suitable to participate in this study.

Design outcomes

Primary

MeasureTime frame
The area under the curve (AUC NRS-R 0-72) of the patient's resting pain score within 0-72 hours after surgery;The incidence of moderate to severe pain, respiratory depression, nausea, and vomiting in PACU 30 minutes after surgery;

Secondary

MeasureTime frame
The AUC (AUC NRS-R 0-72) of pain score during exercise 0-72 hours after surgery and the total amount of rescue analgesics;Patient postoperative recovery quality (QoR-15), first time walking out of bed, time of chest tube extraction, length of hospital stay;The compression time, total number of compressions, and dosage of PCIA used for the first time as a remedial analgesia;

Countries

China

Contacts

Public ContactLi Chao

The Fourth Hospital of Hebei Medical University

jysylichao@163.com+86 138 3111 0738

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026