Pain
Conditions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Age range from 18 to 75 years old; (2) Patients planning to undergo thoracoscopic lung surgery; (3) ASA classification levels I-III; (4) BMI 18~30kg/m^2. (5) Voluntarily participate and sign an informed consent form.
Exclusion criteria
Exclusion criteria: (1) There were already other acute and chronic pains before the surgery; (2) Pregnancy, lactation, or planned pregnancy; (3) There are contraindications to the use of anesthetics, adjunctive analgesics, salvage analgesics, and antiemetic drugs in the study; (4) Long term treatment with opioid drugs or use of any analgesic within 48 hours prior to surgery; (5) Suffering from sleep apnea syndrome; (6) Suffering from mental and neurological disorders, gastrointestinal obstruction, chronic obstructive pulmonary disease or pulmonary heart disease, severe cardiovascular disease, etc; (7) Acute or severe bronchial asthma patients without vital sign monitoring or life resuscitation equipment (8) The researchers believe that participants who are not suitable to participate in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The area under the curve (AUC NRS-R 0-72) of the patient's resting pain score within 0-72 hours after surgery;The incidence of moderate to severe pain, respiratory depression, nausea, and vomiting in PACU 30 minutes after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| The AUC (AUC NRS-R 0-72) of pain score during exercise 0-72 hours after surgery and the total amount of rescue analgesics;Patient postoperative recovery quality (QoR-15), first time walking out of bed, time of chest tube extraction, length of hospital stay;The compression time, total number of compressions, and dosage of PCIA used for the first time as a remedial analgesia; | — |
Countries
China
Contacts
The Fourth Hospital of Hebei Medical University