Periodontal disease
Conditions
Interventions
Laser group:Ultrasound subgingival scaling+laser treatment
control group:Ultrasound subgingival scaling++sham therapy of laser treatment
Sponsors
The Second Affiliated Hospital of Zhejiang University School of Medicine
Eligibility
Sex/Gender
All
Age
30 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Patients aged between 40-75 years old diagnosed with periodontitis and taking anticoagulant drugs (including warfarin and new oral anticoagulants) for more than 6 months 2. The International Normalized Ratio (INR) is less than or equal to 3.5 3. No periodontal basic treatment has been performed in the past six months, including scaling, scraping, flap surgery and other debridement treatments 4. The cardiovascular disease is in a stable period, meaning that there have been no acute cardiovascular events within 6 months 5. No history of surgery or active bleeding in the past year 6. The patient has clear thinking, unobstructed communication, and high compliance 7. The number of teeth that can be retained on one side of the patient's mouth is greater than or equal to 4 teeth
Exclusion criteria
Exclusion criteria: 1. Cardiac function levels III and IV 2. Blood pressure >= 180/110 mmHg 3. Pregnant women, women in pregnancy or lactation period 4. Those who are currently taking drugs known to affect periodontal tissue or have a history of antibacterial treatment within the past 3 months 5. Patients with uncontrolled and stable systemic diseases, such as progressive liver diseases, infectious diseases, severe trauma, renal failure, rheumatoid arthritis, blood system diseases, mental diseases, diabetes, etc 6. Patients with malignant tumors or undergoing radiotherapy, chemotherapy, and targeted drug therapy 7. Patients with pacemakers who cannot undergo ultrasound therapy 8. Smoking or quitting smoking for less than 5 years 9. Patients receiving treatment with bisphosphonates
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| probing depth; | — |
Secondary
| Measure | Time frame |
|---|---|
| clinical attachment level;plaque index;bleeding index;number of loosen teeth;postoperative bleeding indicators;Gum color;Comfort level of treatment;tooth sensitivity; | — |
Countries
China
Contacts
Public ContactLei Lihong
The Second Affiliated Hospital of Zhejiang University School of Medicine
Outcome results
None listed