Neuroimaging evaluation of neonatal hyperbilirubinemia: a single-center predictive study

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2500112001

Enrollment

Unknown

Registered

2025-11-09

Start date

2024-12-13

Completion date

Unknown

Last updated

2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

neonatal hyperbilirubinemia

Interventions

Observation group:None

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: From December 2024 to November 2025, 50 neonates with a gestational age of =35 weeks were admitted to the East Hospital of Shanghai First Maternity and Infant Hospital due to neonatal hyperbilirubinemia within 48 hours to 2 weeks after birth, with a maximum total serum bilirubin level ranging from 342 to 427 µmol/L.

Exclusion criteria

Exclusion criteria: Severe developmental malformations;The parents did not consent to an MRI of the skull.

Design outcomes

Primary

Measure	Time frame
The degree of bilirubin-induced nerve damage;Neurological development outcomes;	—

Secondary

Measure	Time frame
bilirubin-induced neurologic damage;Results of auditory brainstem response (ABR);	—

Countries

China

Contacts

Public ContactXuefeng HU

Shanghai First Maternity and Infant Hospital

1021501215@qq.com+86 20261001

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026