Osteoarthritis
Conditions
Interventions
Normal group:None
Sponsors
The First Affiliated Hospital of Air Force Military Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. All patients were diagnosed as osteoarthritis according to the standardized diagnosis in routine clinical examination (refer to the Chinese guideline for diagnosis and treatment of osteoarthritis ; 2. Chronic pain of hip and knee and stiffness for at least 6 months; 3. Patients with grade?osteophytes on standing anteroposterior knee radiographs; osteophytes, joint space narrowing.
Exclusion criteria
Exclusion criteria: 1. History of previous knee or hip surgery, inflammatory arthritis, crystal arthritis, septic arthritis, rheumatoid arthritis; 2. Contraindications of magnetic resonance imaging; 3. Severe systemic diseases (such as diabetes mellitus, hyperthyroidism, adrenal hypoplasia, systemic lupus erythematosus, ankylosing spondylitis, etc.)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sulfate metabolism-related proteomics;Sulfate metabolism-related transcriptome;Sulfate metabolism-related targeted metabolomics;Expression of proteins associated with sulfur metabolism;Expression of genes related to sulfur metabolism; | — |
Countries
China
Contacts
Public ContactYang Liu
The First Affiliated Hospital of Air Force Military Medical University
Outcome results
None listed